PhD, Georgia Institute of Technology, 2013 - 2017
MSME, Georgia Institute of Technology, 2013 - 2016
BS, Georgia Institute of Technology, 2009 - 2013
Shea, S.M., Mihalko, E.P., Lu, L., Thomas, K.A., Schuerer, D., Brown, J.B., Bochicchio, G.V., & Spinella, P.C. (2024). Doing more with less: low-titer group O whole blood resulted in less total transfusions and an independent association with survival in adults with severe traumatic hemorrhage. J Thromb Haemost, 22(1), 140-151.Elsevier BV. doi: 10.1016/j.jtha.2023.09.025.
Shea, S.M., Reisz, J.A., Mihalko, E.P., Rahn, K.C., Rassam, R.M.G., Chitrakar, A., Gamboni, F., D'Alessandro, A., Spinella, P.C., & Thomas, K.A. (2024). Cold-stored platelet hemostatic capacity is maintained for three weeks of storage and associated with taurine metabolism. J Thromb Haemost, 22(4), 1154-1166.Elsevier BV. doi: 10.1016/j.jtha.2023.11.025.
Mihalko, E.P., Srinivasan, A.J., Rahn, K.C., Seheult, J.N., Spinella, P.C., Cap, A.P., Triulzi, D.J., Yazer, M.H., Neal, M.D., & Shea, S.M. (2023). Hemostatic In Vitro Properties of Novel Plasma Supernatants Produced from Late-storage Low-titer Type O Whole Blood. ANESTHESIOLOGY, 139(1), 77-90.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/ALN.0000000000004574.
Thomas, K.A., Srinivasan, A.J., McIntosh, C., Rahn, K., Kelly, S., McGough, L., Clayton, S., Perez, S., Smith, A., Vavro, L., Musgrove, J., Hill, R., Mdaki, K.S., Bynum, J.A., Meledeo, M.A., Cap, A.P., Spinella, P.C., Reddoch-Cardenas, K.M., & Shea, S.M. (2023). Comparison of platelet quality and function across apheresis collection platforms. TRANSFUSION, 63(S3), S146-S158.Wiley. doi: 10.1111/trf.17370.
Younes, R., Spinella, P.C.C., Shea, S.M.M., Bailey-Kroll, L., Neal, M.D.D., Leeper, C., & Yazer, M.H.H. (2023). A rapid ABO and RhD test demonstrates high fidelity to blood bank testing for RhD typing. TRANSFUSION, 63(S3), S208-S212.Wiley. doi: 10.1111/trf.17326.
Zarisfi, M., Younes, R., Alsaadi, N., Liu, Z., Loughran, P., Williamson, K., Spinella, P.C., Shea, S., Rosengart, M.R., Andraska, E.A., & Neal, M.D. (2023). Long wavelength light exposure reduces systemic inflammation coagulopathy, and acute organ injury following polytrauma in mice. J Trauma Acute Care Surg.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/TA.0000000000004234.
Ashworth, K.J., Thomas, K.A., & Shea, S.M. (2022). Von Willebrand Factor and Platelet Aggregation: from Bench to Clinical Practice. Current Anesthesiology Reports, 12(2), 329-341.Springer Science and Business Media LLC. doi: 10.1007/s40140-022-00521-5.
Han, Q., Shea, S.M., Arleo, T., Qian, J.Y., & Ku, D.N. (2022). Thrombogenicity of biomaterials depends on hemodynamic shear rate. ARTIFICIAL ORGANS, 46(4), 606-617.Wiley. doi: 10.1111/aor.14093.
Shea, S.M., Spinella, P.C., & Thomas, K.A. (2022). Cold-stored platelet function is not significantly altered by agitation or manual mixing. TRANSFUSION, 62(9), 1850-1859.Wiley. doi: 10.1111/trf.17005.
Shea, S.M.M., Thomas, K.A.A., Rassam, R.M.G., Mihalko, E.P.P., Daniel, C., Sullenger, B.A.A., Spinella, P.C.C., & Nimjee, S.M.M. (2022). Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of Arterial Occlusion. PHARMACEUTICALS, 15(12), 1450.MDPI AG. doi: 10.3390/ph15121450.
Spinella, P.C., Bochicchio, K., Thomas, K.A., Staudt, A., Shea, S.M., Pusateri, A.E., Schuerer, D., Levy, J.H., Cap, A.P., & Bochicchio, G. (2022). The risk of thromboembolic events with early intravenous 2-and 4-g bolus dosing of tranexamic acid compared to placebo in patients with severe traumatic bleeding: A secondary analysis of a randomized, double-blind, placebo-controlled, single-center trial. TRANSFUSION, 62(S1), S139-S150.Wiley. doi: 10.1111/trf.16962.
Thomas, K.A., Shea, S.M., Saini, A., Muszynski, J.A., & Spinella, P.C. (2022). Correlation between Thrombin Generation, Standard Coagulation Assays, and Viscoelastic Assays for Hemostatic Assessment in Critically Ill Children. J Appl Lab Med, 7(5), 1108-1119.Oxford University Press (OUP). doi: 10.1093/jalm/jfac030.
Kim, D., Shea, S.M., & Ku, D.N. (2021). Lysis of arterial thrombi by perfusion of N,N'-Diacetyl-L-cystine (DiNAC). PLOS ONE, 16(2), e0247496.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0247496.
Manning, K.B., Nicoud, F., & Shea, S.M. (2021). Mathematical and computational modeling of device-induced thrombosis. CURRENT OPINION IN BIOMEDICAL ENGINEERING, 20, 100349.Elsevier BV. doi: 10.1016/j.cobme.2021.100349.
Tanaka, K.A., Shettar, S., Vandyck, K., Shea, S.M., & Abuelkasem, E. (2021). Roles of Four-Factor Prothrombin Complex Concentrate in the Management of Critical Bleeding. TRANSFUSION MEDICINE REVIEWS, 35(4), 96-103.Elsevier BV. doi: 10.1016/j.tmrv.2021.06.007.
Thomas, K.A., Shea, S.M., & Spinella, P.C. (2021). Effects of pathogen reduction technology and storage duration on the ability of cryoprecipitate to rescue induced coagulopathies in vitro. TRANSFUSION, 61(6), 1943-1954.Wiley. doi: 10.1111/trf.16376.
D'Alessandro, A., Thomas, K.A., Stefanoni, D., Gamboni, F., Shea, S.M., Reisz, J.A., & Spinella, P.C. (2020). Metabolic phenotypes of standard and cold-stored platelets. TRANSFUSION, 60(Suppl 3), S96-S106.Wiley. doi: 10.1111/trf.15651.
Shea, S.M., Staudt, A.M., Thomas, K.A., Schuerer, D., Mielke, J.E., Folkerts, D., Lowder, E., Martin, C., Bochicchio, G.V., & Spinella, P.C. (2020). The use of low-titer group O whole blood is independently associated with improved survival compared to component therapy in adults with severe traumatic hemorrhage. TRANSFUSION, 60(S3), S2-S9.Wiley. doi: 10.1111/trf.15696.
Spinella, P.C., Thomas, K.A., Turnbull, I.R., Fuchs, A., Bochicchio, K., Schuerer, D., Reese, S., Coleoglou Centeno, A.A., Horn, C.B., Baty, J., Shea, S.M., Meledeo, M.A., Pusateri, A.E., Levy, J.H., Cap, A.P., Bochicchio, G.V., & Investigators, T.A.M.P.I.T.I. (2020). The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial. FRONTIERS IN IMMUNOLOGY, 11, 2085.Frontiers Media SA. doi: 10.3389/fimmu.2020.02085.
Barker, E.E., Saini, A., Gazit, A.Z., Shea, S.M., Baltagi, S.A., Gage, B.F., & Spinella, P.C. (2019). TEG Platelet Mapping and Impedance Aggregometry to Predict Platelet Transfusion During Cardiopulmonary Bypass in Pediatric Patients. FRONTIERS IN PEDIATRICS, 7, 509.Frontiers Media SA. doi: 10.3389/fped.2019.00509.
Shea, S.M., Thomas, K.A., & Spinella, P.C. (2019). The effect of platelet storage temperature on haemostatic, immune, and endothelial function: potential for personalised medicine. BLOOD TRANSFUSION, 17(4), 321-330. doi: 10.2450/2019.0095-19.
Thomas, K.A., Shea, S.M., Yazer, M.H., & Spinella, P.C. (2019). Effect of leukoreduction and pathogen reduction on the hemostatic function of whole blood. TRANSFUSION, 59(S2), 1539-1548.Wiley. doi: 10.1111/trf.15175.
Hastings, S.M., Griffin, M.T., & Ku, D.N. (2017). Hemodynamic studies of platelet thrombosis using microfluidics. PLATELETS, 28(5), 427-433.Informa UK Limited. doi: 10.1080/09537104.2017.1316483.
Hastings, S.M., Ku, D.N., Wagoner, S., Maher, K.O., & Deshpande, S. (2017). Sources of Circuit Thrombosis in Pediatric Extracorporeal Membrane Oxygenation. ASAIO JOURNAL, 63(1), 86-92.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/MAT.0000000000000444.
Hastings, S.M., Deshpande, S.R., Wagoner, S., Maher, K., & Ku, D.N. (2016). Thrombosis in centrifugal pumps: location and composition in clinical and in vitro circuits. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 39(4), 200-204.SAGE Publications. doi: 10.5301/ijao.5000498.
Hoteit, L., Mihalko, E., Rahn, K., Steinman, R., Shea, S.M., & Neal, M.D. (2022). Antithrombotic Testing Using Platelet Aggregometry Vs Small Volume Stenotic Microfluidic Device. In BLOOD, 140(Supplement 1), (pp. 13018-13019).American Society of Hematology. doi: 10.1182/blood-2022-169344.
Mihalko, E.P., Shea, S.M., Thomas, K.A., Huff, M., Schuerer, D., Bochicchio, G., & Spinella, P. (2022). Improved Survival in Severely Bleeding Trauma Patients Treated with Low-Titer Group O Whole Blood Compared to Component Therapy. In TRANSFUSION, 62, (pp. 244A-245A).
Srinivasan, A.J., Mihalko, E.P., Rahn, K.C., Seheult, J., Spinella, P., Cap, A.P., Triulzi, D.J., Yazer, M.H., Neal, M.D., & Shea, S.M. (2022). Plasma Supernatants from Late-Storage Low-Titer Type O Whole Blood Have Improved in Vitro Hemostatic Efficacy over Liquid Plasma. In TRANSFUSION, 62, (pp. 67A-68A).
Barker, E., Saini, A., Gazit, A., Baltagi, S., Spinella, P., Gage, B., & Shea, S. (2020). TEG AND IMPEDANCE AGGREGOMETRY TO PREDICT PLATELET TRANSFUSION DURING BYPASS FOR PEDIATRIC PATIENTS. In CRITICAL CARE MEDICINE, 48.
Ku, D.N., Casa, L.D.C., & Hastings, S.M. (2017). Choice of a hemodynamic model for occlusive thrombosis in arteries. In JOURNAL OF BIOMECHANICS, 50, (pp. 110-113).Elsevier BV.United States. doi: 10.1016/j.jbiomech.2016.11.029.
Ku, D.N., Shea, S., Maher, K., & Deshpande, S. (2022). Connector for Flexible Tubing Used for Fluid Transport.
Shea, S., Thomas, K., & Spinella, P. (2022). Compositions and methods for preserving or increasing platelet function.
Kim, D., Ku, D.N., & Shea, S. (2021). Use of cystine and derivatives thereof as anti-thrombotic and thrombolytic agents.