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Supported by: National Institute of Child Health and Human Development |
Useful / Interesting Links: University of Pittsburgh Bioengineering - Department home page and starting point for graduate student applications. Rotating tadpole head (xk81 expression in a 3-D movie) - 3D view of gene expression in epithelium. Nieuwkoop Faber Staging - Frames based staging table. Can take a few minutes to load all the stages. Xenbase - invaluable resource for Xenopus research. W. M. Keck Center for Cellular Imaging - Imaging resource at University of Virginia Center for Biologic Imaging - Imaging resources at University of Pittsburgh. Center for Cellular Dynamics at Friday Harbor Laboratory ImageJ - Excellent cross-platform image processing software (RGB) from Wayne Rasband (NIH) and the worldwide ImageJ community. NIH-Image - Excellent Mac-based image processing software (grey) from Wayne Rasband (NIH) and the worldwide NIH-Image community. Scion-Image - PC port of NIH-Image and Firewire cameras and drivers for ImageJ MetaMorph / Molecular Devices - Image acquisition and processing software Molecular Probes / Invitrogen - source of useful fluorophores.
Literature / Resources: Filla, M. B., Czirok, A., Zamir, E. A., Little, C. D., Cheuvront, T. J., Rongish, B.J. (2004) Dynamic imaging of cell, extracellular matrix, and tissue movements during avian vertebral axis patterning. Birth Defects Res C Embryo Today. 72:267-76. Nice review of early role of cell motility and ECM in Avian morphogenesis. Koehl, M. A. R. (1990). Biomechanical approaches to morphogenesis. Seminars in Developmental Biology 1: 367-78. An excellent primer on biomechanics using neurulation as an example. Trinkaus, J. P. (1984). Cells into Organs: the forces that shape the embryo. Englewood Cliffs, Prentice-Hall Inc. Required reading from the pre-molecular-era. Bray, D. (2001). Cell Movements: From Molecules to Motility. (2nd ed.) New York, Garland Publishing. Pollack, D.H. (2001). Cells, Gels, and the Engines of Life. Ebner and Sons. Stern, C.D., editor (2004). Gastrulation: From Cells to Embryo. Cold Spring Harbor Laboratory Press. web site |