STAGE 52 Age +/- 21 d.; length 42-56 mm.
Ext. Crit.:*Forelimb bud irregularly conical*. *Hindlimb bud showing first indication of ankle constriction and first sign of flattening of foot*.
Int. Crit.: *Sense organs of caudal lateral line appearing on postanal fin*. *"Stirnorgan" situated just cranial to paraphysis*. Dorsal column ("dorsal horn") beginning to appear at postbrachial levels of spinal cord. *Lumbar ganglia with a few large cells*. About 10 Jacobson's glands on organon vomero-nasale.
*Separation of for. acusticum anterius and posterius*. *Chondrification completed in 4th to 9th vertebral arches; chondrification in lateral wall of perichordal tube extending from atlas down to intervertebral region between 2nd and 3rd vertebra*; 3 pairs of ribs discernable as mesenchymatous condensations. *Femur rudiment procartilaginous, tibia and fibula mesenchymatous*; local condensations of mesenchyme indicating beginning of muscle development. *Appearance of arteria subclavia*. *Beginning of sexual differentiation of gonads*.
Small pigment cells appearing in cortical region of thymus. *5 complete revolutions in outer and inner spiral of intestinal helix*.