Pitt HomeEngineering HomeContact Us
School of Engineering

People Robert S. Parker

Associate Professor, Graduate Coordinator

Chemical and Petroleum Engineering

Member, Molecular Therapeutics and Drug Discovery Program, University of Pittsburgh Cancer Institute

Member, McGowan Institute for Regenerative Medicine, University of Pittsburgh Medical School


412-624-7364
Fax: 412-624-9639
Office: 1241 Benedum Hall

Education

PhD University of Delaware, 1999
BS University of Rochester, 1994

Professional Interests

Professor Parker joined the faculty in January 2000 after completing his PhD His research focuses on process modeling, analysis, and control, with an interest in biomedical and biological systems applications.

Specific research project areas in Professor Parker's group include:

  • Cancer tumor growth modeling and optimal therapy
  • Noninvasive measurement of drug pharmacokinetics
  • Diabetic patient modeling and blood glucose regulation
  • Empirical model identification and validation
  • Simultaneous process identification and control

Selected Publications

(full publication list available here)

F.J. Doyle III, D. Seborg, R.S. Parker, B.W. Bequette, A. Jeffrey, X. Xia, I. Craig, and T.J. McAvoy. “A Tutorial on Biomedical Process Control,” J. Process Control (in press).

A.S. Soni and R.S. Parker. “Tailored Input Sequence Design for Third-Order Volterra Model Identification,” Ind. & Eng. Chem. Res. vol. 46 (3), 818-829, 2007.

A. Roy and R.S. Parker. “Dynamic Modeling of Free Fatty Acids, Glucose, and Insulin: An Extended Minimal Model,” Diabetes Technology and Therapeutics 8(6), 617-626, 2006.

J.H. Beumer, E. Joseph, M.J. Egorin, R.S. Parker, D.Z. D’Argenio, J.M. Covey and J.L. Eiseman. “A Mass Balance and Disposition Study of the DNA-methyltransferase Inhibitor Zebularine (NSC 309132) and Three of its Metabolites in Mice.” Clinical Cancer Res. vol. 12 (19), 5826-5833, 2006.

R.S. Parker, F.J. Doyle III, and M.A. Henson. “Integrating Biological Systems Content in the Process Dynamics and Control Curriculum.” Chemical Engineering Education vol. 40 (3), 181-188, 2006.

J.A. Florian, Jr., J.L. Eiseman, and R.S. Parker. “Accounting for Quiescent Cells in Tumor Growth and Cancer Treatment.” FOSBE Conference Special Issue of IEE Systems Biology vol. 152, 185-192, 2005.

J.A. Florian Jr. and R.S. Parker. “Empirical Modeling for Glucose Control in Diabetes and Critical Care.” European Journal of Control, Special Section on Automatic Drug Delivery for Anesthesia and Critical Care, vol. 11 (6), 616-616, 2005.

P.W. Barone, R.S. Parker, and M.S. Strano. “In-Vivo Fluorescence Detection of Glucose using a Single Walled Carbon Nanotube Optical Sensor: Design, Fluorophore Properties, Advantages, and Disadvantages.” Analytical Chemistry vol. 77 (23), 7556-7562, 2005.

J.M. Harrold, W.C. Zamboni, J.L. Eiseman, and R.S. Parker. “A Pharmacokinetic / Pharmacodynamic Model of 9–Nitrocamptothecin in SCID Mice.” J. Pharmacokinetics and Pharmacodynamics vol. 32 (1), 65-83, 2005.

J. J. McCarthy and R. S. Parker. “The Pillars of Chemical Engineering: A Block Scheduled Curriculum.” Chemical Engineering Education vol. 38 (4), pp. 292-301, 2004.

A.S. Soni and R.S. Parker. “Closed-Loop Control of Fed-Batch Bioreactors: A Shrinking-Horizon Approach.” Ind. & Eng. Chem. Res. vol. 43, pp. 3381-3393, 2004.

R.S. Parker, J.M. Harrold, J.L. Eiseman, W.C. Zamboni, E. Joseph, S. Strychor, and M.J. Egorin. "Toward Model-Based Chemotherapy Treatment Design" in Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Volume III. D.Z. D'Argenio (Ed.). Kluwer Academic Publishers; Norwell, MA, pp. 255-274, 2004.

R.S. Parker. "Insulin Delivery" in Encyclopedia of Biomaterials and Biomedical Engineering, G. Wnek and G. Bowlin (Eds.). Marcel Dekker, Inc.; New York, 2003.

J.A. Florian Jr., J.L. Eiseman, and R.S. Parker. "A Nonlinear Model Predictive Control Algorithm for Breast Cancer Treatment." Proc. DYCOPS 7, Boston, MA, 2004. (Keynote Paper & Presentation)

C. Komives and R.S. Parker. "Bioreactor State Estimation and Control." Current Opinions in Biotechnology vol. 14, pp. 468-474, 2003.

 

View funding and awards.

Benedum Hall

Dedicated in 1971, Benedum Hall is home to exploration and discovery.

You are using a browser that does not support current Web standards. Although this site is viewable in all browsers, it will look much better in a browser that supports Web standards.