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Undergraduate Courses BIOENG 1220

BIOENG 1220 - Biotransport Phenomena

Instructor: Patzer

Credits: 3

Term: Fall

Description: Biotransport Phenomena explores the similarities between the fundamental principles of momentum, heat, and mass transfer, develops analogies between the fundamentals that apply at microscopic and macroscopic scales, and uses the fundamentals in conjunction with conservation laws to develop mathematical descriptions of physiological and engineering systems. Especial emphasis is placed on identifying assumptions that may be used in developing the mathematical descriptions.

The course uses an interactive framework developed through the VANTH (Vanderbilt, Northwestern, Texas, and Harvard-MIT) consortium for biomedical engineering curricula development to explore transport phenomena (momentum, heat, and mass transfer) through a series of interactive modules.

Prerequisites: MATH 0250 or 0290, BIOENG 1210

Recommended Texts: R.L. Fournier, Basic Transport Phenomena in Biomedical Engineering, 2nd Ed, 2006.

Supplemental Texts:

  • A.K. Datta, Biological and Bioenvironmental Heat and Mass Transfer, 2002.
  • L. Sherwood, Human Physiology, 5th Ed.

Course Objectives: Upon completing the course, the student should be able to describe the fundamental principles pertaining to momentum, heat, and mass transport and apply the fundamental principles to set up and solve problems in physiological systems and design of medical devices.

Topics Covered: Module topics may include:

  • Factors influencing the Design of a Heart-Lung Machine
  • Cell Fluid Volume Regulation
  • Determinants of Cell Size
  • Postmortem Interval
  • Respiratory Clearance
  • Asthma & COPD
  • Biological Applications of Collapsible and Compliant Tubes
  • Blood Rheology in Sickle Cell Anemia
  • Inert Gas Exchange
  • O2 and CO2 Exchange
  • Design of a Rapid Reaction Apparatus
  • Compartmental Analysis and Pharmacokinetics
  • Designing Components of a Heart-Lung Machine

Syllabus: Microsoft Word Format

Class/Laboratory Schedule: Class meets twice a week for 75 minutes each day. Recitation meets once a week for 75 minutes.

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